BICOSOME® TECHNOLOGY
WORKING WITH THE SKIN, NOT AGAINST IT
The skin is our body’s protective barrier, and its ability to protect itself is one of its most important functions. A strong, healthy skin barrier is essential for maintaining skin health.
As skin scientists, we develop bio-inspired technologies designed to interact with the skin while respecting its natural barrier function. We believe the most effective approach is to work with the skin’s own biological processes, rather than against them. This philosophy inspires the development of our active ingredients and delivery technologies.
Bicosomes® mimic the skin’s own transport system, drawing on the structure and function of lamellar bodies, specialized organelles involved in the transport of lipids within the skin.
When applied to the skin, the outer vesicles of Bicosomes® interact with the skin surface, while their smart lipid structures selectively penetrate through the intercorneocyte spaces, reaching the targeted skin layers where the active ingredients are needed.
Once the active ingredients have been delivered, Bicosome® lipid structures integrate into the skin’s lipid matrix, helping to support and strengthen the skin barrier.
By working with the skin’s natural biology, Bicosomes® enable effective delivery while respecting and supporting the skin barrier.
Dual Structure – HOW IT WORKS:
- The external vesicle fuses
- The smart discs penetrate
- The active is target delivered
- Bicosomes are integrated in the skin matrix
MAIN BENEFITS
Gentle skin penetration- Target delivery
- Reinforcement of skin matrix
- Reduction of irritation
- Stabilisation of molecules
- From natural origin
Gentle skin penetration Target delivery Reinforcement of skin matrix
Reduction of irritation Stabilisation of molecules Boost the efficacy of actives
SKIN DELIVERY BY DESIGN
Bicosome® structures are smart because they can interact with and respond to the different environments within the skin. This enables the targeted delivery of active ingredients to the specific skin layers where they are designed to work, helping maximize their efficacy.
The images below show skin explants treated with four different Bicosome® prototypes, illustrating Bicosome®’s ability to target different skin layers depending on the delivery strategy.
The molecule encapsulated in all prototypes is Sodium Fluorescein (FLU-Na), a hydrophilic fluorescent probe. Its delivery and distribution within the skin were visualized using fluorescence microscopy.
